Perinatal management: What has been learned through the network?

Space and the vestibular system: what has been learned?

What has been learned from computational models of attention

There are few fields where neurocomputational modelling 1 is as necessary as in that of attention — a multifaceted and 2 elusive process that is at the very core of cognition and con3 sciousness (James, 1890). While descriptive theories of at4 tentional functions, relying on a plethora of metaphors (spot5 light/zoomlens, increased-gain, biased-competition), abound, 6 computational models that a...

What has been learned about the cardiovascular effects of matrix metalloproteinases from mouse models?

Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes responsible for extracellular protein degradation in the cardiovascular system. Originally known to play pivotal roles in tissue morphogenesis and wound healing, they have been shown to participate in the complex remodeling processes in blood vessels and the myocardium. The biological activity of MMPs is regulated at different...

Strategies for quantifying the relationship between medications and suicidal behaviour: what has been learned?

In recent years there has been considerable concern that certain classes of drugs, for example antidepressants, may increase the risk of suicide. In this current opinion article, we examine the literature on methodological and statistical approaches to the design and analysis of suicidal event studies. Experimental, ecological and observational studies of the relationship between drugs and suic...

Vaccine effectiveness in older individuals: what has been learned from the influenza-vaccine experience.

Vaccination policies in most high-income countries attempt to reduce the adverse impact of influenza targeting people aged at least 60 years. However, while it is widely believed that the current immunization strategy saves many lives, influenza infection still remains a severe burden in aged individuals leading to a wide debate on the exact magnitude of the benefit of vaccination in this popul...